Lutz Jermutus : rechercher sur Z-Library

Le plus grand référentiel d'articles scientifiques au monde. 70,000,000+ d'articles gratuitement.

Campagne de collecte 15 septembre 2024 – 1 octobre 2024

Z-Library est une des plus grandes bibliothèques en ligne dans le monde, avec le stockage de plus de 17,000,000 livres et plus de 84,837,000 articles. Nous encourageons l'accès libre de chacun à la littérature. Aujourd'hui (15 septembre 2024) nous faisons un appel de fonds à tous ceux qui veulent contribuer encore plus au soutien et au développement de notre projet.

Les téléchargements SANS LIMITE sont aussi (au cours de 31 jours après la date de don) disponibles pour TOUS les utilisateurs qui soient en mesure de soutenir le projet pendant la période de collecte de fonds jusqu'au 1 octobre 2024.

C'est quoi, la collecte de fonds?En savoir plus

Faire un don

Livres
Articles (34)
Les plus populaires
Liste
- Liste
- Tableau

Apelin-36-[L28A] and Apelin-36-[L28C(30kDa-PEG)] peptides that improve diet induced obesity are G Protein Biased Ligands at the Apelin Receptor

Nyimanu, Duuamene, Kuc, Rhoda E., Williams, Thomas L., Bednarek, Maria, Ambery, Philip, Jermutus, Lutz, Maguire, Janet J., Davenport, Anthony P.

Journal:

Peptides

Année:

2019

Langue:

english

Fichier:

PDF, 3.17 MB

english, 2019

Parallel, high-throughput purification of recombinant antibodies for in vivo cell assays

David Bannister, Andrew Wilson, Leah Prowse, Meg Walsh, Rob Holgate, Lutz Jermutus, Trevor Wilkinson

Journal:

Biotechnology and Bioengineering

Année:

2006

Langue:

english

Fichier:

PDF, 357 KB

english, 2006

Isolation of a Small-Molecule Inhibitor of the Antiapoptotic Protein Bcl-xL from a DNA-Encoded Chemical Library

Samu Melkko, Luca Mannocci, Christoph E. Dumelin, Alessandra Villa, Roberto Sommavilla, Yixin Zhang, Markus G. Grütter, Nadine Keller, Lutz Jermutus, Ronald H. Jackson, Jörg Scheuermann, Dario Neri

Journal:

ChemMedChem

Année:

2010

Langue:

english

Fichier:

PDF, 916 KB

english, 2010

Recent advances in producing and selecting functional proteins by using cell-free translation

Lutz Jermutus, Lyubov A Ryabova, Andreas Plückthun

Journal:

Current Opinion in Biotechnology

Année:

1998

Langue:

english

Fichier:

PDF, 1.27 MB

english, 1998

Ligand binding of a ribosome-displayed protein detected in solution at the single molecule level by fluorescence correlation spectroscopy

Lutz Jermutus, Reto Kolly, Zeno Földes-Papp, Jozef Hanes, Rudolf Rigler, Andreas Plückthun

Journal:

European Biophysics Journal

Année:

2002

Langue:

english

Fichier:

PDF, 42 KB

english, 2002

Ligand binding of a ribosome-displayed protein detected in solution at the single molecule level by fluorescence correlation spectroscopy

Lutz Jermutus, Reto Kolly, Zeno Földes-Papp, Jozef Hanes, Rudolf Rigler, Andreas Plückthun

Journal:

European Biophysics Journal

Année:

2002

Langue:

english

Fichier:

PDF, 116 KB

english, 2002

Creating and evaluating protein diversity

Lutz Jermutus, Joelle Pelletier

Journal:

Current Opinion in Biotechnology

Année:

2001

Langue:

english

Fichier:

PDF, 38 KB

english, 2001

Selection of hapten-specific single-domain antibodies from a non-immunized llama ribosome display library

Kerrm Y.F Yau, Maria A.T Groves, Shenghua Li, Claudia Sheedy, Hung Lee, Jamshid Tanha, C.Roger MacKenzie, Lutz Jermutus, J.Christopher Hall

Journal:

Journal of Immunological Methods

Année:

2003

Langue:

english

Fichier:

PDF, 986 KB

english, 2003

Affinity maturation of a VHH by mutational hotspot randomization

Kerrm Y.F. Yau, Ginette Dubuc, Shenghua Li, Tomoko Hirama, C. Roger MacKenzie, Lutz Jermutus, J. Christopher Hall, Jamshid Tanha

Journal:

Journal of Immunological Methods

Année:

2005

Langue:

english

Fichier:

PDF, 196 KB

english, 2005

Harnessing phage and ribosome display for antibody optimisation

Patrick Dufner, Lutz Jermutus, Ralph R. Minter

Journal:

Trends in Biotechnology

Année:

2006

Langue:

english

Fichier:

PDF, 386 KB

english, 2006

Ribosome display: an in vitro method for selection and evolution of antibodies from libraries

Christiane Schaffitzel, Jozef Hanes, Lutz Jermutus, Andreas Plückthun

Journal:

Journal of Immunological Methods

Année:

1999

Langue:

english

Fichier:

PDF, 541 KB

english, 1999

How do you find new drugs using polypeptide display?

Lutz Jermutus, Jane K Osbourn

Journal:

Trends in Biotechnology

Année:

2000

Langue:

english

Fichier:

PDF, 60 KB

english, 2000

Current methods for the generation of human antibodies for the treatment of autoimmune diseases

Jane Osbourn, Lutz Jermutus, Alex Duncan

Journal:

Drug Discovery Today

Année:

2003

Langue:

english

Fichier:

PDF, 113 KB

english, 2003

Expression of high-affinity human antibody fragments in bacteria

Rouet, Romain, Lowe, David, Dudgeon, Kip, Roome, Brendan, Schofield, Peter, Langley, David, Andrews, John, Whitfeld, Peter, Jermutus, Lutz, Christ, Daniel

Journal:

Nature Protocols

Année:

2012

Langue:

english

Fichier:

PDF, 471 KB

english, 2012

Comparison of Escherichia coli and rabbit reticulocyte ribosome display systems

Jozef Hanes, Lutz Jermutus, Christiane Schaffitzel, Andreas Plückthun

Journal:

FEBS Letters

Année:

1999

Langue:

english

Fichier:

PDF, 294 KB

english, 1999

Disordered C-terminal domain of tyrosyl-tRNA synthetase: Secondary structure prediction

Lutz Jermutus, Valérie Guez, Hugues Bedouelle

Journal:

Biochimie

Année:

1999

Langue:

english

Fichier:

PDF, 168 KB

english, 1999

In Vitro Selection for Catalytic Activity with Ribosome Display

Amstutz, Patrick, Pelletier, Joelle N., Guggisberg, Armin, Jermutus, Lutz, Cesaro-Tadic, Sandro, Zahnd, Christian, Plückthun, Andreas

Journal:

Journal of the American Chemical Society

Année:

2002

Langue:

english

Fichier:

PDF, 222 KB

english, 2002

Structure-based chimeric enzymes as an alternative to directed enzyme evolution: phytase as a test case

Lutz Jermutus, Michel Tessier, Luis Pasamontes, Adolphus P.G.M van Loon, Martin Lehmann

Journal:

Journal of Biotechnology

Année:

2001

Langue:

english

Fichier:

PDF, 488 KB

english, 2001

Potency optimization of Huwentoxin-IV on hNav1.7: A neurotoxin TTX-S sodium-channel antagonist from the venom of the Chinese bird-eating spider Selenocosmia huwena

Revell, Jefferson D., Lund, Per-Eric, Linley, John E., Metcalfe, Jacky, Burmeister, Nicole, Sridharan, Sudharsan, Jones, Clare, Jermutus, Lutz, Bednarek, Maria A.

Journal:

Peptides

Année:

2013

Langue:

english

Fichier:

PDF, 782 KB

english, 2013

Ribosome Display Efficiently Selects and Evolves High-Affinity Antibodies in vitro from Immune Libraries

Jozef Hanes, Lutz Jermutus, Susanne Weber-Bornhauser, Hans Rudolf Bosshard and Andreas Pluckthun

Journal:

Proceedings of the National Academy of Sciences

Année:

1998

Langue:

english

Fichier:

PDF, 1.58 MB

english, 1998

Engineering a therapeutic IgG molecule to address cysteinylation, aggregation and enhance thermal stability and expression

Buchanan, Andrew, Clementel, Veronica, Woods, Rob, Harn, Nicholas, Bowen, Michael A, Mo, Wenjun, Popovic, Bojana, Bishop, Steven M., Dall’Acqua, William, Minter, Ralph, Jermutus, Lutz, Bedian, Vahe

Journal:

mAbs

Année:

2013

Langue:

english

Fichier:

PDF, 1013 KB

english, 2013

Challenges and opportunities for non-antibody scaffold drugs

Vazquez-Lombardi, Rodrigo, Phan, Tri Giang, Zimmermann, Carsten, Lowe, David, Jermutus, Lutz, Christ, Daniel

Journal:

Drug Discovery Today

Année:

2015

Langue:

english

Fichier:

PDF, 6.91 MB

english, 2015

Tailored amino acid diversity for the evolution of antibody affinity

González-Muñoz, Andrea, Bokma, Evert, O’Shea, Desmond, Minton, Kevin, Strain, Martin, Vousden, Katherine, Rossant, Christine, Jermutus, Lutz, Minter, Ralph

Journal:

mAbs

Année:

2012

Langue:

english

Fichier:

PDF, 1.88 MB

english, 2012

Apelin-36 Modulates Blood Glucose and Body Weight Independently of Canonical APJ Receptor Signaling

Galon-Tilleman, Hadas, Yang, Hong, Bednarek, Maria A., Spurlock, Sandra M., Paavola, Kevin J., Ko, Brian, To, Carmen, Luo, Jian, Tian, Hui, Jermutus, Lutz, Grimsby, Joseph, Rondinone, Cristina M., Kon

Journal:

Journal of Biological Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 1.09 MB

english, 2017

Inhibition of T-cell activation by the CTLA4-Fc Abatacept is sufficient to ameliorate proteinuric kidney disease

Herrera, Marcela, Söderberg, Magnus, Sabirsh, Alan, Valastro, Barbara, Mölne, Johan, Santamaria, Beatriz, Valverde, Angela M., Guionaud, Silvia, Heasman, Stephanie, Bigley, Alison, Jermutus, Lutz, Ron

Journal:

American journal of physiology. Renal physiology

Année:

2017

Langue:

english

Fichier:

PDF, 2.11 MB

english, 2017

LEAP2 Is an Endogenous Antagonist of the Ghrelin Receptor

Ge, Xuecai, Yang, Hong, Bednarek, Maria A., Galon-Tilleman, Hadas, Chen, Peirong, Chen, Michael, Lichtman, Joshua S., Wang, Yan, Dalmas, Olivier, Yin, Yiyuan, Tian, Hui, Jermutus, Lutz, Grimsby, Josep

Journal:

Cell Metabolism

Année:

2017

Langue:

english

Fichier:

PDF, 2.06 MB

english, 2017

MEDI0382, a GLP-1-glucagon receptor dual agonist, meets safety and tolerability endpoints in a single-dose, healthy-subject, randomised, phase 1 study

Ambery, Philip D., Klammt, Sebastian, Posch, Maximillian G., Petrone, Marcella, Pu, Wenji, Rondinone, Cristina, Jermutus, Lutz, Hirshberg, Boaz

Journal:

British Journal of Clinical Pharmacology

Année:

2018

Langue:

english

Fichier:

PDF, 524 KB

english, 2018

Engineering Neprilysin Activity and Specificity to Create a Novel Therapeutic for Alzheimer’s Disease

Webster, Carl I., Burrell, Matthew, Olsson, Lise-Lotte, Fowler, Susan B., Digby, Sarah, Sandercock, Alan, Snijder, Arjan, Tebbe, Jan, Haupts, Ulrich, Grudzinska, Joanna, Jermutus, Lutz, Andersson, Chr

Journal:

PLoS ONE

Année:

2014

Langue:

english

Fichier:

PDF, 2.66 MB

english, 2014

Hospital admissions for severe infections in people with chronic kidney disease in relation to renal disease severity and diabetes status

Berni, Ellen, Pritchard, Nicholas, Jenkins-Jones, Sara, Ambery, Philip, Jain, Meena, Jermutus, Lutz, Scott, Laura A., Currie, Craig J.

Journal:

Endocrinology, Diabetes & Metabolism

Année:

2018

Langue:

english

Fichier:

PDF, 770 KB

english, 2018

TNFR2 ligation in human T regulatory cells enhances IL2-induced cell proliferation through the non-canonical NF-κB pathway

Wang, Jun, Ferreira, Ricardo, Lu, Wanhua, Farrow, Samatha, Downes, Kate, Jermutus, Lutz, Minter, Ralph, Al-Lamki, Rafia S., Pober, Jordan S., Bradley, John R.

Journal:

Scientific Reports

Année:

2018

Langue:

english

Fichier:

PDF, 2.69 MB

english, 2018

Major adverse cardiovascular events in people with chronic kidney disease in relation to disease severity and diabetes status

Currie, Craig J., Berni, Ellen R., Berni, Thomas R., Jenkins-Jones, Sara, Sinsakul, Marvin, Jermutus, Lutz, Ambery, Philip, Jain, Meena, Bjornstad, Petter

Journal:

PLoS ONE

Année:

2019

Langue:

english

Fichier:

PDF, 3.41 MB

english, 2019

Development and validation of an LC-MS/MS method for detection and quantification of in vivo derived metabolites of [Pyr1]apelin-13 in humans

Nyimanu, Duuamene, Kay, Richard G., Sulentic, Petra, Kuc, Rhoda E., Ambery, Philip, Jermutus, Lutz, Reimann, Frank, Gribble, Fiona M., Cheriyan, Joseph, Maguire, Janet J., Davenport, Anthony P.

Journal:

Scientific Reports

Année:

2019

Langue:

english

Fichier:

PDF, 4.14 MB

english, 2019

Development and validation of an LC-MS/MS method for detection and quantification of in vivo derived metabolites of [Pyr1]apelin-13 in humans

Nyimanu, Duuamene, Kay, Richard G., Sulentic, Petra, Kuc, Rhoda E., Ambery, Philip, Jermutus, Lutz, Reimann, Frank, Gribble, Fiona M., Cheriyan, Joseph, Maguire, Janet J., Davenport, Anthony P.

Journal:

Scientific Reports

Année:

2019

Fichier:

PDF, 4.14 MB

2019

Effects of cotadutide on biomarkers of non-alcoholic steatohepatitis in overweight or obese subjects with type 2 diabetes mellitus: a 54-week analysis of a randomized phase 2b study

Nahra, Rajaa, Gadde, Kishore, Hirshberg, Boaz, Jermutus, Lutz, Maaske, Jill, Stumvoll, Michael, Wang, Tao, Ambery, Philip

Journal:

Journal of Hepatology

Année:

2020

Fichier:

PDF, 125 KB

2020